Couverture : Open Library
Approaches to Gene Mapping in Complex Human Diseases
Résumé
Overview of mapping common and genetically complex human disease traits (J. L. Haines, M. A. Pericak-Vance). Basic concepts in genetics (M. C. Speer). Defining disease phenotypes (A. S. Aylsworth). Basic concepts in linkage analysis ( M. A. Pericak-Vance). Determining the genetic component of a disease (L. A. Farrer, L. A. Cupples). Patient and family participation in genetic research studies (P. E. Cohen, C. Wolpert). Sample size and power (M. C. Speer). The collection of biological samples for DNA analysis (J. M. Vance). Methods of genotyping (J. M. Vance, K. B. Othmane). Database design for gene mapping studies (C. Haynes, C. Blach). Genomic screening (J. L. Haines). Lod score analysis (J. Xu, D. A. Meyers, M. A. Pericak-Vance). Sib pair analysis (D. E. Goldgar). Affected relative pair analysis (J. L. Haines). Linkage disequilibrium and allelic association (M. A. Pericak-Vance). Using public databases (J. L. Haines). Laboratory approaches toward gene identification (D. A. Marchuk). Examining complex genetic interactions (J. M. Schildkraut). Glossary. Appendix: useful websites for genetic analysis. Index.
Détails de l'édition
- ISBN-13
- 9780471171959
- ISBN-10
- 0471171956
- EAN
- 9780471171959
- Éditeur
- Wiley-Liss (New York)
- Date de publication
- 8 octobre 1998
- Langue
- en
- Pages
- 472
- Dimensions
- 25 cm
Provenance des données
- dimensions BnF Catalogue général · 23 juillet 2026
- language Google Books · 8 septembre 2026
- page_count Google Books · 8 septembre 2026
- publication_date Google Books · 8 septembre 2026
- summary Google Books · 8 septembre 2026
- title Google Books · 8 septembre 2026